1: Recenti Prog Med. 2008 Jul-Aug;99(7-8):343-6.
[Antibiotic treatment of pyelonephritis in children. Recent advances][Article in Italian]
Dipartimento di Pediatria, Azienda Ospedaliera, Padova. email@example.com
Urinary tract infection (UTI) is one of the most common bacterial infections in infancy, its prevalence being 5% in febrile infants (2 to 24 months of age). 10 to 20% of febrile UTIs may result in permanent renal damage (scar), whose long-term significance (hypertension or proteinuria) in previously normal kidneys remains unclear. A wide variety of antibiotic agents have been used, generally administered aggressively by intravenous route and for long periods (up to three weeks), to possibly prevent scar formation and/or sepsis complications. Recent studies suggest that children with febrile UTIs can be effectively treated with oral antibiotics such as cefixime or amoxycillin/clavulanic acid for 10 to 14 days.
Related ArticlesTreatment of urinary tract infections among febrile young children with daily intravenous antibiotic therapy at a day treatment center. [Pediatrics. 2004] ReviewAntibiotic treatment for urinary tract infections in pediatric patients. [Minerva Pediatr. 2003] ReviewAntibiotics for acute pyelonephritis in children. [Cochrane Database Syst Rev. 2007] Early treatment of acute pyelonephritis in children fails to reduce renal scarring: data from the Italian Renal Infection Study Trials. [Pediatrics. 2008] [Comparative study of cefixime versus amoxicillin-clavulanic acid combination in the oral treatment of urinary tract infections in children] [Arch Pediatr. 1995] » See Reviews... | » See All...
2.-Indian J Pediatr. 2008 Aug;75(8):809-14. Epub 2008 Sep 4. Links
Advances in management of urinary tract infections.Prajapati BS, Prajapati RB, Patel PS.
Sheth L, G. General Hospital, Aakanksha Children Hospital and Neonatal Nursery, Ahmedabad, India. firstname.lastname@example.org
Urinary Tract Infections (UTI) are a common bacterial infection in children. The diagnosis of UTI is very often missed in young children due to minimal and non-specific symptoms. The developing renal cortex in young children is vulnerable to renal scarring resulting in hypertension and chronic renal failure. A clinically suspected case of UTI should be defined and documented with urine culture report. After the diagnosis of UTI, its category should be defined. It will guide for proper radioimaging evaluation, choice of antimicrobial agent, duration of treatment, need of chemoprophylaxis etc. Even a single confirmed UTI should be taken seriously. Rational use of modern radioimaging for proper evaluation is essential. UTI in neonates, nosocomial UTI and UTI due to ESBL producing organisms are special situations, to be identified and managed with advanced therapy promptly and appropriately.
4.- Antibiotic prophylaxis for childhood urinary tract infection: a national survey.
Chevalier I, Benoît G, Gauthier M, Phan V, Bonnin AC, Lebel MH.
J Paediatr Child Health. 2008 Oct;44(10):572-8.
PMID: 19012629 [